[2017]

・Co-instillation of nano-solid magnesium hydroxide enhances corneal permeability of dissolved timolol. Nagai N., Ogata F., Otake H., Kawasaki N., Nakazawa Y., Kanai K., Okamoto N. and Shimomura Y. 2017. Exp. Eye Res. 165: 118-124.

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・Rebamipide suppresses TNF-α production and macrophage infiltration in the conjunctiva.Tajima K, Hattori T, Takahashi H, Katahira H, Narimatsu A, Kumakura S, Goto H. 2017. Vet Ophthalmol. 21(4): 347-352.

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・Mesenchymal Stem Cells Contribute to Hepatic Maturation of Human Induced Pluripotent Stem Cells. Takagi C, Yagi H, Hieda M, Tajima K, Hibi T, Abe Y, Kitago M, Shinoda M, Itano O, Kitagawa Y. 2017. Eur Surg Res. 58: 27-39.

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・The Aldosterone Receptor Antagonist Eplerenone Inhibits Isoproterenol-Induced Collagen-I and 11β-HSD1 Expression in Rat Cardiac Fibroblasts and the Left Ventricle. Hori Y, Touei D, Saitoh R, Yamagishi M, Kanai K, Hoshi F, Itoh N. 2017. Biol Pharm Bull. 40: 1716-1723.

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・ Repeated phlebotomies decrease body iron storage in adult dogs.Chikazawa S, Hoshi F, Kanai K. 2017. J Vet Med Sci. 79: 1652-1655.

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・ A Nanoparticle-Based Ophthalmic Formulation of Dexamethasone Enhances Corneal Permeability of the Drug and Prolongs Its Corneal Residence Time.Nagai N, Nakazawa Y, Ito Y, Kanai K, Okamoto N, Shimomura Y. 2017. Biol Pharm Bull. 40: 1055-1062.

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[2016]​

・Endocrine pancreas engineered using porcine islets and partial pancreatic scaffolds. Katsuki Y, Yagi H, Okitsu T, Kitago M, Tajima K, Kadota Y, Hibi T, Abe Y, Shinoda M, Itano O, Takeuchi S, Kitagawa Y. 2016. Pancreatology. 16: 922-30.

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・Heterotopic transplantation of a decellularized and recellularized whole porcine heart. Kitahara H, Yagi H, Tajima K, Okamoto K, Yoshitake A, Aeba R, Kudo M, Kashima I, Kawaguchi S, Hirano A, Kasai M, Akamatsu Y, Oka H, Kitagawa Y, Shimizu H. 2016. Interact Cardiovasc Thorac Surg. 22: 571-9.

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・Indirect arterial blood pressure measurement in healthy anesthetized cats using a device that combines oscillometry with photoplethysmography. Heishima Y, Hori Y, Chikazawa S, Kanai K, Hoshi F, Itoh N. J Vet Med Sci. 2016 Aug 1;78(7):1179-82.

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・Influence of storage conditions on in vitro stability of atrial natriuretic peptide and of anesthesia on plasma atrial natriuretic peptide concentration in cats. Heishima Y, Hori Y, Chikazawa S, Kanai K, Hoshi F, Itoh N. Am J Vet Res. 2016 Aug;77(8):854-9.

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・Luteolin attenuates endotoxin-induced uveitis in Lewis rats. Kanai K, Hatta T, Nagata S, Sugiura Y, Sato K, Yamashita Y, Kimura Y, Itoh N. J Vet Med Sci. 2016 Sep 1;78(8):1229-35.

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・Molecular detection and characterization of Cryptosporidium spp. among breeding cattery cats in Japan. Ito Y, Itoh N, Kimura Y, Kanai K. Parasitol Res. 2016 May;115(5):2121-3.

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・Plasma atrial natriuretic peptide and N-terminal pro B-type natriuretic peptide concentrations in dogs with right-sided congestive heart failure. Kanno N, Hori Y, Hidaka Y, Chikazawa S, Kanai K, Hoshi F, Itoh N. J Vet Med Sci. 2016 May 3;78(4):535-42.

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・Prevalence of intestinal parasites in breeding cattery cats in Japan. Ito Y, Itoh N, Kimura Y, Kanai K. J Feline Med Surg. 2016 Oct;18(10):834-7.

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・Relative potency of tyrosol in the treatment of endotoxin-induced uveitis in rats. Sato K, Mihara Y, Kanai K, Yamashita Y, Kimura Y, Itoh N. J Vet Med Sci. 2016 Nov 1;78(10):1631-1634.

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・Therapeutic anti-inflammatory effects of luteolin on endotoxin-induced uveitis in Lewis rats. Kanai K, Nagata S, Hatta T, Sugiura Y, Sato K, Yamashita Y, Kimura Y and Itoh N The Journal of Veterinary Medical Science 78(8) 1384 2016.

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・Tyrosol ameliorates lipopolysaccharide-induced ocular inflammation in rats via inhibition of nuclear factor (NF)-κB activation. Sato K, Mihara Y, Kanai K, Yamashita Y, Kimura Y, Itoh N. J Vet Med Sci. 2016 Oct 1;78(9):1429-1438.

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・結膜に生じた扁平上皮乳頭種の犬の１例　佐藤和昭、金井一享*、畑井仁、古林与志安、山下洋平、木村裕哉、伊藤直之 動物臨床医学 25(3) 105-108 2016

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[2015]

・Hyperferritinemia is associated with short survival time in dogs with multicentric lymphoma. Chikazawa S., Hori Y., Hoshi F., Kanai K. and Ito N. 2015. J. Vet. Med. Sci. 77: 843-846.

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・Two Different Concentrations of Topical Levofloxacin for the Treatment of Multidrug-Resistant Pseudomonas aeruginosa Keratitis.Tajima K, Miyake T, Koike N, Hattori T, Takahashi H, Matsumoto T, Fujita K, Kuroda M, Ito N, Goto H. 2015. J Ocul Pharmacol Ther. 31: 636-41.

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・Novel primary epithelial cell toxicity assay using porcine corneal explants.Takahashi H, Tajima K, Hattori T, Yamakawa N, Ito N, Goto H. 2015. Cornea. 34: 567-75.

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・AFM characterization of chemically treated corneal cells. Shibata-Seki T, Tajima K, Takahashi H, Seki H, Masai J, Goto H, Kobatake E, Akaike T, Itoh N. 2015. Anal Bioanal Chem. 407: 2631-5.

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・Prevalence of intestinal parasites in breeding kennel dogs in Japan. Itoh N, Kanai K, Kimura Y, Chikazawa S, Hori Y, Hoshi F. Parasitol Res. 2015 Mar;114(3):1221-4.

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[2014]

・Effect of the phosphodiesterase type 5 inhibitor tadalafil on pulmonary hemodynamics in a canine model of pulmonary hypertension. Hori Y, Kondo C, Matsui M, Yamagishi M, Okano S, Chikazawa S, Kanai K, Hoshi F, Itoh N. Vet J. 2014 Nov;202(2):334-9.

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・Erythrophagocytosis enhances heme-dependent cytotoxicity of antimalarial drugs in canine histiocytic sarcoma cell line DH82. Chikazawa S, Kitahara Y, Ando E, Hori Y, Hoshi F, Kanai K, Ito N, Higuchi S. J Vet Med Sci. 2014 Mar 1;76(2):249-53.

 

・Molecular detection and characterization of Cryptosporidium species in household dogs, pet shop puppies, and dogs kept in a school of veterinary nursing in Japan. Itoh N, Oohashi Y, Ichikawa-Seki M, Itagaki T, Ito Y, Saeki H, Kanai K, Chikazawa S, Hori Y, Hoshi F, Higuchi S. Vet Parasitol. 2014 Mar 1;200(3-4):284-8.​

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・重度の反復する下部消化管出血に対して大腸血管拡張症を疑った犬の1例　近澤征史朗、畑井仁、後藤晃伸　2014.日獣会誌 67: 767-772.

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​[2013]

・Change in serum ferritin concentration in experimentally induced anemia of chronic inflammation in dogs. Chikazawa S, Nakazawa T, Hori Y, Hoshi F, Kanai K, Ito N, Orino K, Watanabe K, Higuchi S. J Vet Med Sci. 2013 Nov;75(11):1419-26.

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・Development of a sandwich enzyme-linked immunosorbent assay to detect and measure serum levels of canine ferritin. Chikazawa S, Hori Y, Hoshi F, Kanai K, Ito N, Sato J, Orino K, Watanabe K, Higuchi S. J Vet Med Sci. 2013 May 2;75(4):515-7.

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・Factors influencing measurement of serum iron concentration in dogs: diurnal variation and hyperferritinemia. Chikazawa S, Hori Y, Kanai K, Ito N, Hoshi F, Orino K, Watanabe K, Higuchi S. J Vet Med Sci. 2013 Dec 30;75(12):1615-8.

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・Hyperferritinemia in dogs with splenic hemangiosarcoma. Chikazawa S, Hori Y, Hoshi F, Kanai K, Ito N, Higuchi S. J Vet Med Sci. 2013 Nov;75(11):1515-8.

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・In vivo challenging of polymyxins and levofloxacin eye drop against multidrug-resistant Pseudomonas aeruginosa keratitis. Tajima K, Miyake T, Koike N, Hattori T, Kumakura S, Yamaguchi T, Matsumoto T, Fujita K, Kuroda M, Ito N, Goto H. 2013. J Infect Chemother. 20: 343-9.

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・Peroxisome proliferator-activated receptor-γ agonist pioglitazone suppresses experimental autoimmune uveitis. Okunuki Y, Usui Y, Nakagawa H, Tajima K, Matsuda R, Ueda S, Hattori T, Kezuka T, Goto H. 2013. Exp Eye Res. 116: 291-7.

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・Prevalence of intestinal parasites in pet shop kittens in Japan. Itoh N, Ito Y, Kato A, Kanai K, Chikazawa S, Hori Y, Hoshi F, Higuchi S. J Feline Med Surg. 2013 Oct;15(10):908-10.

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・Methicillin-resistant Staphylococcus aureus keratitis in a dog. Tajima K, Sinjyo A, Ito T, Noda Y, Goto H, Ito N. Veterinary ophthalmology. 2013 May;16(3):240-3.

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​[2012]

・Effects of instillation of eyedrops containing disulfiram and hydroxypropyl-β-cyclodextrin inclusion complex on endotoxin-induced uveitis in rats. Kanai K, Ito Y, Nagai N, Itoh N, Hori Y, Chikazawa S, Hoshi F, Higuchi S. Curr Eye Res. 2012 Feb;37(2):124-31.

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・Matrix metalloproteinase-2 stimulates collagen-I expression through phosphorylation of focal adhesion kinase in rat cardiac fibroblasts. Hori Y, Kashimoto T, Yonezawa T, Sano N, Saitoh R, Igarashi S, Chikazawa S, Kanai K, Hoshi F, Itoh N, Higuchi S. Am J Physiol Cell Physiol. 2012 Nov 1;303(9):C947-53.

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・Myocardial injury-related changes in plasma NT-proBNP and ANP concentrations in a canine model of ischemic myocardial injury. Hori Y, Ohshima N, Chikazawa S, Kanai K, Hoshi F, Itoh N, Higuchi S. Vet J. 2012 Jan;191(1):46-51.

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・Prevalence of intestinal parasites in private-household cats in Japan. Itoh N, Ikegami H, Takagi M, Ito Y, Kanai K, Chikazawa S, Hori Y, Hoshi F, Higuchi S. J Feline Med Surg. 2012 Jun;14(6):436-9.

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[2011]

・Anti-inflammatory potency of oral disulfiram compared with dexamethasone on endotoxin-induced uveitis in rats. Kanai K, Itoh N, Ito Y, Nagai N, Hori Y, Chikazawa S, Hosi F, Higuchi S J. Vet. Med. Sci. 73(4) 517-520 2011

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・Clinical implications of measurement of plasma atrial natriuretic peptide concentration in dogs with spontaneous heart disease. Hori Y, Yamano S, Kanai K, Hoshi F, Itoh N, Higuchi S. J Am Vet Med Assoc. 2011 Oct 15;239(8):1077-83.

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・Giardia and other intestinal parasites in dogs from veterinary clinics in Japan. Itoh N, Kanai K, Tominaga H, Kawamata J, Kaneshima T, Chikazawa S, Hori Y, Hoshi F, Higuchi S. Parasitol Res. 2011 Jul;109(1):253-6.

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・Molecular cloning and expression analysis of feline α1-microglobulin. Nakata J, Nakahari A, Kato Y, Yamachi N, Sato N, Yonezawa T, Takahashi C, Chikazawa S, Hori Y, Kanai K, Ito N, Higuchi S, Hoshi F. Vet Immunol Immunopathol. 2011 Jan;139(1):79-82.

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・Prevalence of intestinal parasites and genotyping of Giardia intestinalis in pet shop puppies in east Japan. Itoh N, Itagaki T, Kawabata T, Konaka T, Muraoka N, Saeki H, Kanai K, Chikazawa S, Hori Y, Hoshi F, Higuchi S. Vet Parasitol. 2011 Feb 28;176(1):74-8.

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・Spironolactone decreases isoproterenol-induced ventricular fibrosis and matrix metalloproteinase-2 in rats. Hori Y, Yoshioka K, Kanai K, Hoshi F, Itoh N, Higuchi S. Biol Pharm Bull. 2011,34(1):61-5

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[2010]

・Acute cardiac volume load-related changes in plasma atrial natriuretic peptide and N-terminal pro-B-type natriuretic peptide concentrations in healthy dogs. Hori Y, Sano N, Kanai K, Hoshi F, Itoh N, Higuchi S. Vet J. 2010 Sep;185(3):317-21.

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・Differences in the duration of diuretic effects and impact on the renin-angiotensin-aldosterone system of furosemide in healthy dogs. Hori Y, Ohshima N, Kanai K, Hoshi F, Itoh N, Higuchi S. J Vet Med Sci. 2010 Jan;72(1):13-8.

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・Inhibitory effects of oral disulfiram on endotoxin-induced uveitis  in rats. Kanai K, Itoh N, Yoshioka K, Yonezawa T, Ikadai H,  Ito Y, Nagai N, Hori Y, Chikazawa S, Hosi F, Higuchi S Curr. Eye Res. 35(10) 892-899 2010

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・Molecular cloning, expression in Escherichia coli, and development of monoclonal antibodies to feline cystatin C. Nakata J, Nakahari A, Takahashi C, Chikazawa S, Hori Y, Kanai K, Ito N, Higuchi S, Hoshi F. Vet Immunol Immunopathol. 2010 Dec 1;138(3):231-4.

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​[2009]

・A case of multiple uveal cysts associated with persistent pupillary  membrane in dog. Kanai K, Fujisawa A, Ikeguchi M, Hori Y, Shimamura S, Nakao R, Hoshi F, Okano S, Itoh N, Higuchi S Anim. Eye Res. 27(1) 39-41 2009

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・Doxycycline attenuates isoproterenol-induced myocardial fibrosis and matrix metalloproteinase activity in rats. Hori Y, Kunihiro S, Sato S, Yoshioka K, Hara Y, Kanai K, Hoshi F, Itoh N, Higuchi S. Biol Pharm Bull. 2009 Oct;32(10):1678-82.

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・Fenbendazole treatment of dogs with naturally acquired Strongyloides stercoralis infection. Itoh N, Kanai K, Hori Y, Nakao R, Hoshi F, Higuchi S. Vet Rec. 2009 May 2;164(18):559-60.

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・Prevalence of Giardia intestinalis and other zoonotic intestinal parasites in private household dogs of the Hachinohe area in Aomori prefecture, Japan in 1997, 2002 and 2007. Itoh N, Kanai K, Hori Y, Hoshi F, Higuchi S. J Vet Sci. 2009 Dec;10(4):305-8.

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・Structural characterization of Tn916-like element in Streptococcus parauberis serotype II strains isolated from diseased Japanese flounder. Meng F, Kanai K, Yoshikoshi K. Lett Appl Microbiol. 2009 Jun;48(6):770-6.

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・The relationship between invasive hemodynamic measurements and tissue Doppler-derived myocardial velocity and acceleration during isovolumic relaxation in healthy dogs. Hori Y, Kunihiro S, Kanai K, Hoshi F, Itoh N, HiguchiI S. J Vet Med Sci. 2009 Nov;71(11):1419-25.

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・超音波検査により水晶体血管膜過形成遺残/第一次硝子体過形成 遺残と診断した犬の1例　金井一享、堀泰智、村田佳瑛子、島村俊介、星史雄、伊藤直之、樋口誠一 日獣会誌 62(9) 720-723 2009

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​[2008]

・Assessing diastolic function with Doppler echocardiography using a novel index: ratio of the transmitral early diastolic velocity to pulmonary diastolic velocity. Hori Y, Kanai K, Nakao R, Hoshi F, Higuchi S. J Vet Med Sci. 2008 Apr;70(4):359-66.

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・Assessment of diuretic effects and changes in plasma aldosterone concentration following oral administration of a single dose of furosemide or azosemide in healthy dogs. Hori Y, Katou A, Tsubaki M, Kanai K, Nakao R, Hoshi F, Itoh N, Higuchi S. Am J Vet Res. 2008 Dec;69(12):1664-9. 

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・Circadian variations in salivary chromogranin a concentrations during a 24-hour period in dogs. Kanai K, Hino M, Hori Y, Nakao R, Hoshi F, Itoh N, Higuchi S. J Vet Sci. 2008 Dec;9(4):421-3.

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・Comparison of the responses of peritoneal macrophages from Japanese flounder (Paralichthys olivaceus) against high virulent and low virulent strains of Edwardsiella tarda. Ishibe K, Osatomi K, Hara K, Kanai K, Yamaguchi K, Oda T. Fish Shellfish Immunol. 2008 Feb;24(2):243-51.

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・Evaluation of plasma C-terminal atrial natriuretic peptide in healthy cats and cats with heart disease. Hori Y, Yamano S, Iwanaga K, Kano T, Tanabe M, Uechi M, Kanai K, Nakao R, Hoshi F, Higuchi S. J Vet Intern Med. 2008 Jan-Feb;22(1):135-9.